This repository does not contain the NONMEM program source
code (except for user-supplied routines, e.g. PRED routines,
written by individual NONMEM users). The NONMEM source code
is copyrighted by the Regents of the University of of California.
Individuals desiring to license NONMEM program source code
should contact: nminfo@globomaxnm.com
The repository is organized by directories. The current directories
are listed in the index below. We encourage the repository
to be used to share user-supplied NONMEM codes, NONMEM data
sets of interest, NM-TRAN control streams, frontend and backend
programs to the NONMEM system, and the like. One might, for
example, contribute NONMEM files (except possibly proprietary
data) used to implement a particular application of interest
e.g. an analysis of both the PK and PD data from a study of
brain-wave activity with the administration of thiopental.
Please feel free to browse through the repository. The repository
is read-only. We would very much appreciate your contributing
files to the repository. Please forward your files to nmconsult@globomaxnm.com
and we'll make them available on the ftp server. Presence
of any file on the ftp server does not imply endorsement of
it's use by GloboMax LLC. Suitability of any file for use
is determined by the individual user and is the responsibility
of the individual user.
The NONMEM repository is maintained by GloboMax LLC and is
independent of the NONMEM Project Group. In addition to new
materials, the repository contains material originally maintained
by Steve Shafer and Jaap Mandema while at the Stanford University
Department of Anesthesia.
Thank you for your interest in the NONMEM respository. We
hope you will use this repository to share with others your
work with NONMEM.
MIXTURE MODEL FOR ASSIGNING RELIABILITY
TO PK OBSERVATIONS AND ESTIMATING INDIVIDUAL PK PARAMETERS
Continuous & cateogorical:
Simultaneous continuous and cateogorical
modelling contributed by Nick
Holford
Discussions:
Notes on Concentrations below the limits
of detection
Help.Dos.Tools:
The files in this directory comprise the
disk labelled "NONMEM Help Guide - DOS tools - May 1996"
This disk is distributed along with NONMEM Guide VIII.
Hf0304.dir:
This directory contains a single file,
hf0304.zip. This file is the patch required in Microsoft
Fortran 5.1 to open more than 25 files simultaneously,
as required for NONMEM. ***OBSOLETE COMPILER***
JWM:
This directory contains NONMEM control
files for various applications(NONMEM IV)
Models for categorical data applied to analgesia
data
PRED routines for 3-compartment models with multiple
drug infusions contributed by Jaap W Mandema
Michaelis-Menten:
control stream for a two compartment model
with parallel first order elimination and Michaelis-Menten
elimination. For straight MM just remove the linear contribution,
contributed by Bill
Bachman
NMREPORT:
a VMS procedure (together with a couple
of FORTRAN programs) that run sequences of NONMEM jobs,
computes AIC and SBC criteria for model comparisons, creates
one output file for all the models.
!!! It will work ONLY with VMS !!! contributed by Ekaterina
Gibiansky
NMSEE:
a post-processor program for NONMEM output.
Nmsee extracts important lines from the NONMEM output.
It can be instructed to ignore certain lines, to reformat
them, and to precede them with identifying prefixes. It
has been revised for NONMEM V, contributed by Alison Boeckmann
NMVCL:
A PRED for 1,2, and 3 compartment mammillary
pharmacokinetic models in terms of volumes and clearance.
Covariates are entered into the model by use of an external
table that relates thetas and covariates to the individual
volume and clearance terms, contributed by Steve Shafer
NON_CONTINUOUS:
Meant to contain control files for non-contiuous
type data such as counts, proportions, time-to-event,
categorical. Currently contains control files for time-to-event
and (binary) categorical. contributed by Lewis
Sheiner
TIPS:
NONMEM Tips of the Week contributed by
GloboMax LLC
Output:
NONMEM output files obtained using:
NONMEM V Level 1.1
Compaq Visual Fortran Optimizing Compiler Version
6.6 (/optimize:1/fpe:0)
PRODUCTS:
NONMEM® USER TIPS