PRODUCTS: NONMEM® USER TIPS

These tips are brought to you as information of interest from experiences in using NONMEM. All tips can also be found in the tips folder on the NONMEM Repository@GloboMax.

Tip # 19 - Notes of the Installation and use of NONMEM V with Intel Fortran 8.0 for Windows:

NONMEM may successfully be installed and used with Intel Fortran 8.0 for
Windows but it is a somewhat problematic process. Some specific comments:

1. Intel Fortran 8.0 requires the purchase and installation of Visual Studio
C++ .Net 2003 which in itself is a rather lengthy but relatively
trouble-free process. It required the installation of Service Pack 4 on
Windows 2000 and other "pre-requisites" which were supplied on a separate
CD-ROM. (Installation of IIS and FrontPage Server Extensions was skipped
without any repercussions). "Step3" of the Visual Studio C++ .Net
installation, the installation of the msdn library and Visual C++ help files
may also be omitted in the interest of saving disk space. The Standard
Edition of Visual Studio C++ .Net 2003 was sufficient for Intel Fortran 8.0
installation.

2. The second release of Intel Fortran 8.0 (w_fc_bc_8[1].0.036.exe) must be
used. The first distribution was released without the ability to compile at
the command line using wildcards!

C:\nmi8\nm>ifort /c *.for
Intel(R) Fortran Compiler for 32-bit applications, Version 8.0 Build
20031017Z Package ID: w_fc_p_8.0.035
Copyright (C) 1985-2003 Intel Corporation. All rights reserved.

error: can't open file *.obj for write
compilation aborted for *.for (code 1)

This was corrected in the second release.

3. Setting the environmental variables is also troublesome. The Intel
Fortran 8.0 installation programs allows you to "Automatically define Intel
Fortran environmental variables". However, this does NOT set the variables
for the system's DOS environment, it sets them for the "Build Environment
for Fortran IA-32 applications" that is accessed via the Programs menu. The
procedure I used to set the environment for the system's DOS environment was
to open a DOS window, record the existing environment, set the environment
for Intel Fortran by using the Intel-supplied ifortvars.bat file, re-record
the environment, compare the environments before and after running
ifortvars.bat with respect to the PATH, LIB and INCLUDE variables, and
finally make the necessary changes to these variables in the USER
environmental variables (not the SYSTEM environmental variables) using the
Control Panel. Thereafter, the DOS environment was correct for running
"ifort", the command line instruction for the compiler. (Detailed
instructions on this step can be supplied on request.)

4. NONMEM was installed using the currently distributed version of setup.bat
(version 4.0) after all 18 instances of "ifl" were replaced with "ifort".
The command line arguments used were "setup a c nmv ifort y". The
replacement of "ifl" was not strictly necessary, but it supressed the
warning message:

ifl: warning: The Intel Fortran driver is now named ifort. You can suppress
this message with '-quiet'
Intel(R) Fortran Compiler for 32-bit applications, Version 8.0 Build
20031211Z Package ID: w_fc_pc_8.0.036
Copyright (C) 1985-2003 Intel Corporation. All rights reserved.

5. The NONMEM installation created in this manner was fully compatible with
PDx-Pop use.

(This tip is supplied "gratis" and without implicit or explicit support from
GloboMax LLC).