PRODUCTS: NONMEM® USER TIPS

These tips are brought to you as information of interest from experiences in using NONMEM. All tips can also be found in the tips folder on the NONMEM Repository@GloboMax.

Tip # 18 - Alison's nmsee5 for summarizing NONMEM output:

This tip is to remind users of a free utility written by Alison Boeckmann
for summarizing NONMEM output. The code for this utility, nmsee5.for, and
instructions are available at:

ftp://ftp.globomaxnm.com/Public/nonmem/nmsee/

To use the utility, compile the fortran code to create the executable
nmsee5.exe, e.g.:
c:\nmv\run> df nmsee5.for
Then redirect the result file of a NONMEM or PDx-Pop run to the nmsee5.exe
program:

c:\nmv\run> nmsee5 < 101.res

The output will be sent to the console and look something like this:

PROBLEM NO. 1
aspirin 1CMT model w. lag
INITIAL ESTIMATE OF THETA:
9.00E+01 6.00E+02 4.60E+00 2.30E-01
LOWER BOUND ON THETA:
0.00E+00 0.00E+00 0.00E+00 0.00E+00
UPPER BOUND ON THETA:
1.00E+06 1.00E+06 1.00E+06 1.00E+06
INITIAL ESTIMATE OF OMEGA:
1.50E-01
0.00E+00 2.60E-01
INITIAL GRADIENT:
-2.04E+03 -1.15E+02 1.83E+02 -3.30E+02 -3.12E+02 -1.52E+01
FINAL GRADIENT:
1.57E-02 -1.14E-01 -1.44E-01 8.63E-01 3.77E-02 -1.10E-02
FINAL PARAMETER:
1.20E-01 1.06E-01 7.36E-02 1.11E-01 1.19E-01 -7.68E-06
MINIMIZATION SUCCESSFUL
NO. OF FUNCTION EVALUATIONS USED: 139
NO. OF SIG. DIGITS IN FINAL EST.: 4.0
MINIMUM VALUE OF OBJECTIVE FUNCTION
109.784
FINAL PARAMETER ESTIMATE
THETA - VECTOR OF FIXED EFFECTS
1.29E+02 6.74E+02 2.49E+00 2.82E-01
OMEGA - COV MATRIX FOR RANDOM EFFECTS - ETAS
2.14E-01
0.00E+00 1.53E-09

The output of nmsee5.exe can also be saved to a file as follows:

c:\nmv\run> nmsee5 < 101.res > 101.sum

A variety of command line options are available for use with nmsee5 and are
described in the directions.

(This tip is supplied "gratis" and without implicit or explicit support from GloboMax LLC).